The
taxonomy browser is an original data analysis tool
for visualizing the taxonomic relationships among the prokaryotes.
The relationships
are based on the evolutionary distances between the organisms,
as
measured
using the small subunit ribosomal RNA (SSU rRNA) molecule
which are visualized using techniques drawn from the field
of exploratory
data analysis. Our preferred
methods of analysis include 2-D maps based on principal
components analysis (PCA), and heatmaps (also known as
shaded distance matrices
or Eisen
plots
when
applied
to
microarray data) with the range of colors representing the
range of distances.
The
coherence
of
taxa can
be evaluated visually and taxonomic and nomenclatural
(annotation) errors can be readily spotted using this approach.
The taxonomy
browser™ is
based on
code written in the S-Plus™ language (Insightful)
and implemented using the S engine to produce stand-alone java applets
and StatServer™ for
interactive applications.
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